Health effects of tea have been recognized since ancient times. For many centuries, green tea has been consumed and used medicinally in India, China, Japan and other Asian countries.
All types of tea – green, black, and oolong – are produced from the Camellia sinensis plant using different methods. The difference among them is how they are processed. The type of tea produced depends on the length of fermentation of the leaves – green tea is not fermented, black tea is nearly completely fermented, while Oolong tea is partially fermented. Fresh leaves from the Camellia sinensis plant are steamed to produce green tea.
Green tea and green tea extracts, such as its component epigallocatechin-3-gallate (EGCG), a polyphenolic compound from green tea, have been used to prevent and treat a variety of cancers, including breast, stomach, and skin cancers.
Green tea and green tea extracts have also been used for improving mental alertness, aiding in weight loss, lowering cholesterol levels, and protecting skin from sun damage.
Green tea is usually brewed and drunk as a beverage. Green tea extracts can be taken in capsules and are sometimes used in skin products.
Santosh Katiyar, PhD, MS
After studying the topic for 16 years, VA (Veterans Affairs) scientist Santosh Katiyar, PhD, MS, is convinced that green tea, because of its rich polyphenol content, is among the most potent tumor-inhibitors that nature provides.
Katiyar reviewed the latest biomedical findings on green tea and skin cancer, including those from his own animal studies at the Birmingham VA and University of Alabama. He outlined five mechanisms through which green tea’s most prevalent and active polyphenol – a robust antioxidant called epigallocatechin-3-gallate, or EGCG – appears to protect the skin from ultraviolet (UV) radiation and prevent tumor formation.
“The polyphenols in green tea have strong antioxidant and anti-inflammatory properties,” said Katiyar, “but more importantly, they enhance the production of interleukin-12, which has a role in DNA repair. If green tea polyphenols can repair DNA, then they can prevent skin cancer.”
Preparing the perfect cup
Santosh Katiyar is a native of India who became a U.S. citizen in the 1990s. He drinks two cups a day of green tea. He says people with fairer skin, who are at higher risk for skin cancer, may need to drink up to six cups per day to derive benefit.
For the perfect cup of tea, he advises that people boil water, remove it from the heat, and then steep the leaves, covered, for four or five minutes. “In that time, most of the polyphenols will dissolve in the warm water. If you boil it with the leaves in it, the polyphenols may get oxidized and polymerized and reduce their activity.”
Santosh Katiyar, who has been funded by VA as well as the National Center for Complimentary and Alternative Medicine and National Cancer Institute, believes military personnel may be at special risk for skin cancer, given their increased exposure to sunlight. That is part of what motivated him to join VA in 2003 and conduct research on behalf of veterans. More than a decade earlier, his initial passion for exploring natural cancer therapies had centered on quite a different population: mothers.
“I lost my mother to breast cancer,” Katiyar said. “I had done my PhD in nutrition, and I realized that my parents had devoted a lot of time and energy to my education. Yet, I could not help my mother. So I resolved to do something to help all the other mothers who are still here. I decided I would work on cancer – how it can be prevented, particularly by dietary supplements and nutrients.”
U.S. Food and Drug Administration (FDA)
These and other lab results may be compelling, but as far as the U.S. Food and Drug Administration is concerned, the jury is still out, pending stronger clinical evidence. A 2005 statement appearing on the FDA website asserts, “Existing evidence does not support qualified health claims for green tea consumption and a reduced risk of prostate, breast, or any other type of cancer.”
Side Effects and Cautions for Some People
- Green tea is safe for most adults when used in moderate amounts.
- There have been some case reports of liver problems in people taking concentrated green tea extracts. This problem does not seem to be connected with green tea infusions or beverages. Although these cases are very rare and the evidence is not definitive, experts suggest that concentrated green tea extracts be taken with food, and that people should discontinue use and consult a doctor if they have a liver disorder or develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice.
- Green tea and green tea extracts contain caffeine. Caffeine can cause insomnia, anxiety, irritability, upset stomach, nausea, diarrhea, or frequent urination in some people.
- Green tea contains small amounts of vitamin K, which can make anticoagulant drugs, such as warfarin, less effective.
Tell your doctor about any complementary and alternative practices you use, and a full picture of what you do to manage your health. This will help ensure coordinated and safe care.
Source: nccam.nih.gov November 2008 and www.research.va.gov Oct 2009